-Source-USAToday- Where Americans live can have a considerable impact on their quality of life. In some U.S. cities everyday comfort and happiness is much harder to attain than in others. Quality of life is subjective and difficult to measure. Still there is a wide range of quantifiable factors that can impact quality of life in a given area. Affordability safety job market strength quality of education infrastructure average commute times air quality and the presence of cultural attractions are just a few examples of factors that can influence overall quality of life. 24/7 Wall St. created an index with measures in eight categories -- crime economy education environment health housing infrastructure and leisure -- to identify the 50 worst cities to live in. Not confined to a single region the worst cities span the country from the South to the Midwest and from New England to the Pacific coast.